0001104659-07-058734 Sample Contracts

AMENDMENT NO. 2
Confidential Treatment • August 3rd, 2007 • Cubist Pharmaceuticals Inc • Pharmaceutical preparations

Cardinal Health PTS, LLC (“Cardinal Health”) and Cubist Pharmaceuticals, Inc., (“Cubist”) are parties to a Processing Services Agreement dated August 11, 2004, as amended by Amendment No. 1 dated May 23, 2005 (the “Agreement”).

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THIRD AMENDMENT TO LEASE
Lease • August 3rd, 2007 • Cubist Pharmaceuticals Inc • Pharmaceutical preparations • Massachusetts

THIS THIRD AMENDMENT TO LEASE (this “Third Amendment”) is made as of the 28th day of June, 2007 (the “Third Amendment Date”), by and between THE REALTY ASSOCIATES FUND VI, L.P., a Delaware limited partnership (“Landlord”) and CUBIST PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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