LICENSE AND COLLABORATION AGREEMENTLicense and Collaboration Agreement • November 9th, 2007 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware
This License and Collaboration Agreement (the “License Agreement” or the “Agreement”) is entered into as of the 6th day of September 2007 (the “Effective Date”) by and among Alnylam Pharmaceuticals, Inc., a Delaware corporation, with its principal place of business at 300 Third Street, Cambridge, Massachusetts 02142 (“Alnylam”), Isis Pharmaceuticals, Inc., a Delaware corporation, with its principal place of business at 1896 Rutherford Road, Carlsbad, California 92008 (“Isis”, and each of Alnylam and Isis, a “Licensor” and together, the “Licensors”), and Regulus Therapeutics LLC, a Delaware limited liability company, with its principal place of business at 1896 Rutherford Road, Carlsbad, California 92008 (“Regulus”).
COLLABORATION AND LICENSE AGREEMENT between ISIS PHARMACEUTICALS, INC. and ORTHO MCNEIL, INC.Collaboration and License Agreement • November 9th, 2007 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York
THIS COLLABORATION AND LICENSE AGREEMENT (the “Agreement”) is made and entered into this September 12, 2007 (the “Execution Date”), by and between Ortho McNeil, Inc., a New Jersey Corporation (“OMI”) having a place of business at 1000 US Route 202, Raritan, New Jersey, 08869 and Isis Pharmaceuticals, Inc., a Delaware Corporation (“Isis”) having a place of business at 1896 Rutherford Road, Carlsbad, California 92008. OMI and Isis each may be referred to herein individually as a “Party,” or collectively as the “Parties.”
LIMITED LIABILITY COMPANY AGREEMENT OF REGULUS THERAPEUTICS LLCLimited Liability Company Agreement • November 9th, 2007 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Massachusetts
This LIMITED LIABILITY COMPANY AGREEMENT (this “Agreement”) of Regulus Therapeutics LLC, a Delaware limited liability company (the “Company”), is entered into as of September 6, 2007 (the “Effective Date”) by and among the Company, Alnylam Pharmaceuticals, Inc., a Delaware corporation (“Alnylam”), and Isis Pharmaceuticals, Inc., a Delaware corporation (“Isis,” and together with Alnylam, the “Members”).
