0001104659-07-083184 Sample Contracts

Second Amended and Restated Employment Agreement
Employment Agreement • November 14th, 2007 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • Illinois

THIS EMPLOYMENT AGREEMENT (this “Agreement”) made effective as of the 13th day of November 2007 (the “Effective Date”), by and between Advanced Life Sciences, Inc., an Illinois corporation (the “Company”), and Michael T. Flavin (the “Executive”).

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Amended and Restated Employment Agreement
Employment Agreement • November 14th, 2007 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • Illinois

THIS EMPLOYMENT AGREEMENT (this “Agreement”) made effective as of the 13th day of November 2007 (the “Effective Date”), by and between Advanced Life Sciences, Inc., an Illinois corporation (the “Company”), and Michael J. Cogan (the “Executive”).

FOURTH AMENDMENT TO LICENSE AGREEMENT
License Agreement • November 14th, 2007 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances)

This FOURTH AMENDMENT TO LICENSE AGREEMENT (this “Amendment”) is entered into as of this 13th day of November, 2007 by and between Advanced Life Sciences Holdings, Inc., a Delaware corporation (“ALS”), and Abbott Laboratories, an Illinois corporation (“Abbott”) to amend the terms of that certain License Agreement dated December 13, 2004 between Abbott and ALS (the “Agreement”).

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