0001104659-08-011194 Sample Contracts

AMENDMENT TO COMMON STOCK PURCHASE AGREEMENT
Common Stock Purchase Agreement • February 15th, 2008 • Metabasis Therapeutics Inc • Pharmaceutical preparations • New York

THIS AMENDMENT TO COMMON STOCK PURCHASE AGREEMENT (this “Amendment”) is made and entered into as of February 15, 2008, by and between METABASIS THERAPEUTICS, INC., a Delaware corporation (the “Company”), and Kingsbridge Capital Limited, an entity organized and existing under the laws of the British Virgin Islands (“Kingsbridge”), with respect to the Common Stock Purchase Agreement dated as of November 2, 2006, by and between the Company and Kingsbridge (the “Purchase Agreement”). Capitalized terms used but not otherwise defined herein shall have the meanings given them in the Purchase Agreement.

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