STRATEGIC ALLIANCE MASTER AGREEMENT AMONG IBIS BIOSCIENCES, INC. ISIS PHARMACEUTICALS, INC. AND ABBOTT MOLECULAR INC.Strategic Alliance Master Agreement • May 12th, 2008 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware
THIS STRATEGIC ALLIANCE MASTER AGREEMENT (this “Master Agreement”) is made and entered into as of this 30th day of January, 2008, by and among Isis Pharmaceuticals, Inc., a Delaware corporation (“Isis”), Ibis Biosciences, Inc., a Delaware corporation (“Ibis”), Abbott Molecular Inc., a Delaware corporation (“AMI”) and Affiliate of Abbott Laboratories, an Illinois corporation (“Abbott”). Ibis, Isis and AMI are sometimes referred to herein individually as a “Party,” and collectively as the “Parties.”
AMENDED AND RESTATED COLLABORATION AND LICENSE AGREEMENTCollaboration and License Agreement • May 12th, 2008 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware
This Amended and Restated Collaboration and License Agreement (the “Agreement”) between ISIS PHARMACEUTICALS, INC. of 1896 Rutherford Road, Carlsbad, CA 92008, USA (“ISIS”) and ANTISENSE THERAPEUTICS LTD., ACN 095 060 745 of Level 1, 10 Wallace Avenue, Toorak, Victoria 3142, AUSTRALIA (“ATL”) is entered into and made effective as of February 8, 2008 (the “Amendment Date”).
LICENSE AND RESEARCH AGREEMENTStock Purchase Agreement • May 12th, 2008 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York
This License and Research Agreement (together with all Exhibits, Schedules and other attachments hereto, this “Agreement”), is dated as of the 7th day of January, 2008 (the “Execution Date”), by and between Genzyme Corporation, a Massachusetts corporation (“Genzyme”) and Isis Pharmaceuticals, Inc., a Delaware corporation (“Isis”). Genzyme and Isis each may be referred to herein individually as a “Party” or collectively as the “Parties.”
CALL OPTION AGREEMENT BY AND AMONG ISIS PHARMACEUTICALS, INC., IBIS BIOSCIENCES, INC. AND ABBOTT MOLECULAR INC. January 30, 2008Call Option Agreement • May 12th, 2008 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware
THIS STOCK PURCHASE AGREEMENT (this “Agreement”) is made and entered into as of this [ ] day of [ , ], by and among Isis Pharmaceuticals, Inc., a Delaware corporation (“Isis”), Ibis Biosciences, Inc., a Delaware corporation and majority owned subsidiary of Isis (“Ibis”), and Abbott Molecular Inc., a Delaware corporation (“AMI”) and Affiliate of Abbott Laboratories, an Illinois corporation (“Abbott”). AMI, Ibis and Isis are sometimes referred to herein individually as a “Party” and collectively as the “Parties.”
VLA4 PARTNER SUPPORT AGREEMENTVla4 Partner Support Agreement • May 12th, 2008 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • New York
This VLA4 PARTNER SUPPORT AGREEMENT (the “Agreement”), entered into as of February 8, 2008 (the “Effective Date”), is made by and between ISIS Pharmaceuticals, Inc., a Delaware corporation with a principal place of business at 1896 Rutherford Road, Carlsbad, CA 92008 (“ISIS”) and TEVA Pharmaceutical Industries Ltd., a limited liability company organized under the laws of Israel with its principal place of business at Petah Tiqva 49131, Israel (“TEVA”).
