0001104659-08-064246 Sample Contracts

FIRST SUPPLEMENTAL INDENTURE
First Supplemental Indenture • October 15th, 2008 • Sciele Pharma, Inc. • Pharmaceutical preparations • New York

This FIRST SUPPLEMENTAL INDENTURE (this “Supplemental Indenture”), by and between SCIELE PHARMA, INC., a Delaware corporation (the “Company”), and LASALLE BANK NATIONAL ASSOCIATION, as trustee under the Indenture referred to below (the “Trustee”) is effective as of October 9, 2008 (the “Effective Date”). Terms used herein but not otherwise herein defined have the meanings assigned to them in the Indenture.

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