0001104659-08-078403 Sample Contracts

LICENSE AGREEMENT BY AND BETWEEN ELI LILLY AND COMPANY AND UNITED THERAPEUTICS CORPORATION DATED NOVEMBER 14, 2008
License Agreement • December 24th, 2008 • United Therapeutics Corp • Pharmaceutical preparations • New York

THIS LICENSE AGREEMENT (the “Agreement”) is made and entered into as of November 14, 2008 (the “Execution Date”), effective as of the Effective Date, by and between Eli Lilly and Company, an Indiana corporation, having its principal place of business at Lilly Corporate Center, Indianapolis, Indiana 46285, (“Lilly”) and United Therapeutics Corporation, a Delaware corporation, having its principal place of business at 1110 Spring Street, Silver Spring, Maryland 20910 (“United Therapeutics”). Lilly and United Therapeutics are referred to individually as a “Party” and collectively as the “Parties.”

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MANUFACTURING AND SUPPLY AGREEMENT BY AND BETWEEN ELI LILLY AND COMPANY, LILLY DEL CARIBE, INC. AND UNITED THERAPEUTICS CORPORATION DATED NOVEMBER 14, 2008
Manufacturing and Supply Agreement • December 24th, 2008 • United Therapeutics Corp • Pharmaceutical preparations

THIS MANUFACTURING AND SUPPLY AGREEMENT (the “Agreement”) is made and entered into as of November 14, 2008 (the “Execution Date”), effective as of the Effective Date, by and between Eli Lilly and Company, an Indiana corporation, having its principal place of business at Lilly Corporate Center, Indianapolis, Indiana 46285, (“Lilly”) and Lilly del Caribe, Inc., a Cayman Island corporation, having its principal place of business at Km 12.6 65th Infantry Avenue, Carolina, PR 00985, (“Lilly del Caribe”) and United Therapeutics Corporation, a Delaware corporation, having its principal place of business at 1110 Spring Street, Silver Spring, Maryland 20910 (“United Therapeutics”). Lilly, Lilly del Caribe and United Therapeutics are referred to individually as a “Party” and collectively as the “Parties.”

STOCK PURCHASE AGREEMENT between Eli Lilly and Company (the “Purchaser”) and United Therapeutics Corporation (the “Company”),
Stock Purchase Agreement • December 24th, 2008 • United Therapeutics Corp • Pharmaceutical preparations • Delaware

THIS STOCK PURCHASE AGREEMENT (this “Agreement”), dated as of November 14, 2008, is made by and between Eli Lilly and Company, an Indiana corporation (the “Purchaser”), and United Therapeutics Corporation, a Delaware corporation (the “Company”).

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