0001104659-09-004443 Sample Contracts

COMMON STOCK SUBSCRIPTION AGREEMENT
Common Stock Subscription Agreement • January 28th, 2009 • Exact Sciences Corp • Services-commercial physical & biological research • Massachusetts

THIS COMMON STOCK SUBSCRIPTION AGREEMENT (the “Agreement”) is made as of January 27, 2009 by and between EXACT Sciences Corporation, a Delaware corporation (the “Company”), and Genzyme Corporation, a Massachusetts corporation (the “Investor”).

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COLLABORATION, LICENSE and PURCHASE AGREEMENT BETWEEN GENZYME CORPORATION AND EXACT SCIENCES CORPORATION
Collaboration, License and Purchase Agreement • January 28th, 2009 • Exact Sciences Corp • Services-commercial physical & biological research • Massachusetts

THIS COLLABORATION, LICENSE and PURCHASE AGREEMENT (this “Agreement”), dated as of January 27, 2009 (the “Effective Date”), is by and between Genzyme Corporation, a Massachusetts corporation (“Genzyme”) and EXACT Sciences Corporation, a Delaware corporation (“EXACT”).

ASSIGNMENT, SUBLICENSE, CONSENT AND EIGHTH AMENDMENT TO LICENSE AGREEMENT
License Agreement • January 28th, 2009 • Exact Sciences Corp • Services-commercial physical & biological research • Delaware

This ASSIGNMENT, SUBLICENSE, CONSENT AND EIGHTH AMENDMENT TO LICENSE AGREEMENT (this “ASSIGNMENT, SUBLICENSE AND AMENDMENT”) is made and entered into as of January 27, 2009, by and among EXACT Sciences Corporation, a Delaware corporation (“EXACT”), Genzyme Corporation, a Massachusetts corporation (“GENZYME”) and Johns Hopkins University, a Maryland corporation (“JHU”). Unless otherwise indicated, all capitalized terms used herein and not otherwise defined shall have the meanings given them in the AGREEMENT (as defined below).

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