0001104659-09-004444 Sample Contracts

AMENDED AND RESTATED LICENSE AGREEMENT by and between GENZYME CORPORATION and EXACT SCIENCES CORPORATION (formerly EXACT LABORATORIES, INC.) January 27, 2009
License Agreement • January 28th, 2009 • Exact Sciences Corp • Services-commercial physical & biological research • Massachusetts

THIS AMENDED AND RESTATED LICENSE AGREEMENT effective as of the Closing Date (defined below) (the “Effective Date”) is by and between Genzyme Corporation, a Massachusetts corporation having its principal offices at 500 Kendall Street, Cambridge, MA 02142 (“Genzyme”), through Genzyme’s Genetics Division (formerly through its Molecular Oncology Division), and EXACT Sciences Corporation (formerly EXACT Laboratories, Inc.), a Delaware corporation having its principal offices at 100 Campus Drive, Marlborough, MA 01752 (“EXACT”).

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