0001104659-09-057375 Sample Contracts

Contract
Supplemental Indenture • October 2nd, 2009 • Celldex Therapeutics, Inc. • In vitro & in vivo diagnostic substances • New York

THIS SUPPLEMENTAL INDENTURE, dated as of September 30, 2009 (this “Supplemental Indenture”), is by and among CuraGen Corporation (the “Company”), Celldex Therapeutics, Inc. (“Parent”) and The Bank of New York Mellon (formerly, The Bank of New York), as trustee under the indenture referred to below (the “Trustee”).

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