0001104659-10-019603 Sample Contracts

4,200,000 Shares EXACT SCIENCES CORPORATION COMMON STOCK ($0.01 PAR VALUE PER SHARE) UNDERWRITING AGREEMENT
Underwriting Agreement • April 14th, 2010 • Exact Sciences Corp • Services-commercial physical & biological research • Wisconsin

Exact Sciences Corporation, a Delaware corporation (the “Company”), proposes to issue and sell to the Underwriter named in Schedule I hereto (the “Underwriter”) 4,200,000 shares of the common stock, par value $0.01 per share, of the Company (the “Firm Shares”).

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