0001104659-10-061909 Sample Contracts

AMENDMENT NO. 1 TO AMENDED AND RESTATED INVESTOR RIGHTS AGREEMENT
Investor Rights Agreement • December 9th, 2010 • Helicos Biosciences Corp • Pharmaceutical preparations • Delaware

This Amendment No. 1 (this “Amendment”) to the Amended and Restated Investor Rights Agreement (the “IRA”), dated as of March 1, 2006, by and between Helicos BioSciences Corporation, a Delaware corporation (the “Company”), and the Investors specified therein, is made and entered into as of November 16, 2010. Capitalized terms used and not otherwise defined herein shall have the respective meanings ascribed to them in the IRA.

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