0001104659-11-021879 Sample Contracts

THIRD AMENDMENT TO COMMERCIAL LEASE
Commercial Lease • April 22nd, 2011 • Synta Pharmaceuticals Corp • Pharmaceutical preparations

Duffy Hartwell LLC, as successor in interest to Duffy Hartwell Limited Partnership, (“LESSOR”) and Synta Pharmaceuticals Corporation, as successor in interest to Shionogi BioResearch Corp., (“LESSEE”) (the LESSOR and the LESSEE are collectively referred to as the “Parties” in this Third Amendment) are landlord and tenant, respectively, under a certain Commercial Lease dated November 4, 1996 (“Initial Lease Agreement”), as amended by a First Amendment to Commercial Lease dated August 30, 2006 (“First Amendment”), as amended by a Second Amendment to Commercial Lease dated May 27, 2008 (“Second Amendment”) (the Initial Lease Agreement, First Amendment, and Second Amendment shall be collectively referred to herein as “Lease Agreement”) for that certain premises containing approximately 34,520 rentable square feet, more or less (the “Leased Premises”), in the building located at 45 Hartwell Avenue, Lexington, MA (the “Building”) and hereby agree as follows:

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