0001104659-11-063904 Sample Contracts

MASTER AMENDMENT TO RESEARCH AND DEVELOPMENT COLLABORATION, OPTION AND LICENSE AGREEMENT
Research and Development Collaboration, Option and License Agreement • November 14th, 2011 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations • New York

This MASTER AMENDMENT TO RESEARCH AND DEVELOPMENT COLLABORATION, OPTION AND LICENSE AGREEMENT (this “Amendment”) is entered into and made effective as of the 2nd day of September, 2011 (the “Amendment Effective Date”) by and between Anacor Pharmaceuticals, Inc., a Delaware corporation having its principal place of business at 1020 East Meadow Circle, Palo Alto, CA 94303 (“Anacor”), and GlaxoSmithKline, LLC (formerly known as SmithKline Beecham Corporation), a Delaware Limited Liability company having offices at One Franklin Plaza, Philadelphia, PA 19101 (“GSK”).

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FIFTH AMENDMENT TO LEASE
Lease • November 14th, 2011 • Anacor Pharmaceuticals Inc • Pharmaceutical preparations

THIS FIFTH AMENDMENT TO LEASE (this “Amendment”), dated for reference purposes as of October 4, 2011, is made and entered into by and between BALZER FAMILY INVESTMENTS, L.P., a California limited partnership (formerly HDP Associates, LLC) (“Lessor”), and ANACOR PHARMACEUTICALS, INC., a Delaware corporation (formerly AnaMax, Inc.) (“Lessee”).

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