0001104659-12-000923 Sample Contracts

7,000,000 Shares Synta Pharmaceuticals Corp. Common Stock UNDERWRITING AGREEMENT
Underwriting Agreement • January 6th, 2012 • Synta Pharmaceuticals Corp • Pharmaceutical preparations • New York

The foregoing will not apply to the registration of the offer and sale of the Shares, and the sale of the Shares to the underwriters, in each case as contemplated by the Underwriting Agreement. In addition, the foregoing restrictions shall not apply to (A) sales of Shares pursuant to sales plans entered into prior to the date hereof pursuant to Rule 10b5-1 under the Exchange Act, up to a maximum amount as set forth across from the undersigned’s name on the schedule attached hereto as Annex B, or (B) (i) the transfer of Shares or Related Securities by gift, (ii) the transfer of Shares or Related Securities to a trust whose beneficiaries consist exclusively of one or more of the undersigned and/or an immediate family member, (iii) the transfer of Shares or Related Securities by will or intestate succession to the legal representative, heir, beneficiary or an immediate family member or (iv) as distributions to members, partners or stockholders of the undersigned; provided, however, that i

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