0001104659-12-051460 Sample Contracts

AMENDMENT No. 4 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH LICENSE AGREEMENT
And Research License Agreement • July 26th, 2012 • Exact Sciences Corp • Services-commercial physical & biological research • Mayo

This Amendment No. 4 (this “Amendment”) to the Mayo Foundation for Medical Education and Research License Agreement dated June 12, 2009 (“Agreement”), is entered into between MAYO Foundation for Medical Education and Research, a Minnesota charitable corporation, located at 200 First Street SW, Rochester, Minnesota 55905-0001 (“MAYO”) and Exact Sciences Corporation, a for-profit company located at 441 Charmany Drive, Madison, WI 53719 (“EXACT”). This Amendment is effective as of May 15, 2012 (“Amendment Effective Date”).

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