0001104659-12-057005 Sample Contracts

SECOND AMENDMENT TO AGREEMENT
Agreement • August 10th, 2012 • Vivus Inc • Pharmaceutical preparations

This Second Amendment to the Agreement (hereinafter referred to as this “Amendment”) is made and effective as of the 1st day of August, 2012 by and between MITSUBISHI TANABE PHARMA CORPORATION (formerly known as Tanabe Seiyaku Co., Ltd.), a corporation with its principal office at 6-18, Kitahama 2-chome, Chuo-ku, Osaka, 541-8505, Japan (hereinafter referred to as “MTPC”), and VIVUS, INC., a corporation with its principal office at 1172 Castro Street, Mountain View, California, 94040, United States of America (hereinafter referred to as “VIVUS”).

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