0001104659-14-024609 Sample Contracts

CLINICAL TRIAL SERVICES AGREEMENT AMENDMENT NO. 4 TO WORK STATEMENT NB-1
Clinical Trial Services Agreement • April 1st, 2014 • Radius Health, Inc. • Blank checks

Pursuant to Section 2.3, 2.11 and 11.7 of the Agreement, the parties wish to enter into this Amendment No. 4 to Work Statement NB-1 (“Amendment No. 4”) effective as of March 28, 2014 (“Amendment Date”). Capitalized terms used in this Amendment No. 4 and not defined herein are used with the meanings ascribed to them in the Agreement and Work Statement NB-1.

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AMENDMENT NO. 2 TO AMENDED AND RESTATED STOCK ISSUANCE AGREEMENT
Stock Issuance Agreement • April 1st, 2014 • Radius Health, Inc. • Blank checks • Massachusetts

RADIUS HEALTH, INC., a Delaware corporation (“Radius”), and NORDIC BIOSCIENCE CLINICAL DEVELOPMENT VII A/S, a Danish corporation (“NB”), are parties to that certain Amended and Restated Stock Issuance Agreement dated as of May 16, 2011 (as amended, the “Agreement”). Pursuant to Section 8.3(b) of the Agreement, Radius and NB wish to enter into this Amendment No. 2 to the Agreement (“Amendment No. 2”) effective as of March 28, 2014 (“Amendment Date”). Capitalized terms used in this Amendment No. 2 and not defined herein shall have the meanings ascribed to them in the Agreement.

AMENDMENT NO. 1 TO SERIES B-2 CONVERTIBLE PREFERRED STOCK AND WARRANT PURCHASE AGREEMENT
Series B-2 Convertible Preferred Stock and Warrant Purchase Agreement • April 1st, 2014 • Radius Health, Inc. • Blank checks • Massachusetts

This Amendment No. 1, dated as of March 28, 2014 (the “Amendment”), by and among Radius Health, Inc., a Delaware corporation (the “Corporation”), and the Series B-2 Majority Investors, amends that certain Series B-2 Convertible Preferred Stock and Warrant Purchase Agreement, dated February 14, 2014, by and among the Corporation and the Investors referenced therein (the “Agreement”). Capitalized terms used in this Amendment without definition shall have the same meaning as set forth in the Agreement unless otherwise indicated.

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