0001104659-14-036103 Sample Contracts

AMENDING AGREEMENT
Commercial Manufacturing Agreement • May 8th, 2014 • Insmed Inc • Pharmaceutical preparations • New York

This Amending Agreement (this “Amending Agreement”) is entered into and effective this 13th day of March, 2014 (the “Effective Date”), by and between Therapure Biopharma Inc. (“Therapure”), a Canadian corporation with its principal place of business in Mississauga, Ontario and Insmed Incorporated (“Insmed”), a Virginia corporation, having its principal office at 9 Deer Park Drive, Suite C, Monmouth Junction, New Jersey. Each of Therapure and Insmed is referred to herein as a “party” and collectively as the “parties”.

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CONTRACT MANUFACTURING AGREEMENT
Contract Manufacturing Agreement • May 8th, 2014 • Insmed Inc • Pharmaceutical preparations • New York

This Contract Manufacturing Agreement (this “Agreement”) is entered into and effective this 7th day of February, 2014 (the “Effective Date”), by and between Therapure Biopharma Inc. (“Therapure”), a Canadian corporation with its principal place of business in Mississauga, Ontario and Insmed Incorporated (“Insmed”), a Virginia corporation, having its principal office at 9 Deer Park Drive, Suite C, Monmouth Junction, New Jersey. Each of Therapure and Insmed is referred to herein as a “party” and collectively as the “parties”.

March 26, 2014 Renu Gupta Executive VP Development & Chief Medical Officer Insmed Incorporated Monmouth Junction, NJ 08852 Dear Renu:
Transition and Separation Agreement • May 8th, 2014 • Insmed Inc • Pharmaceutical preparations • New Jersey

This letter confirms our mutual agreement regarding the terms and conditions of your transition and separation (“Transition and Separation Agreement”) from employment with Insmed, Inc. (“Insmed” or the “Company”). You and the Company agree as follows:

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