0001104659-14-043096 Sample Contracts

AGREEMENT
Rights Agreement • June 2nd, 2014 • Senomyx Inc • Services-commercial physical & biological research • Delaware

This Agreement (this “Agreement”) is entered into effective as of May 30, 2014 by and between RIMA Senvest Management, LLC (“RIMA”), Senvest Master Fund, L.P. (“Master Fund”), Richard Mashaal, (“Richard”), Senvest International L.L.C. (“International,” and together with RIMA, Master Fund, Richard and any Affiliate or Associate thereof, “Senvest”) and Senomyx, Inc., a Delaware corporation (the “Company”). Capitalized terms not defined herein will have the meaning given in the Rights Agreement between the Company and Mellon Investor Services LLC, as Rights Agent, dated as of February 14, 2005 and amended as of the date of this Agreement (the “Rights Agreement”).

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FIRST AMENDMENT TO RIGHTS AGREEMENT
Rights Agreement • June 2nd, 2014 • Senomyx Inc • Services-commercial physical & biological research • Delaware

This FIRST AMENDMENT (the “Amendment”) to the Rights Agreement (the “Agreement”) entered into as of February14, 2005, by and between SENOMYX, INC., a Delaware corporation (the “Company”), and COMPUTERSHARE INC. (the “Rights Agent”), successor-in-interest to Mellon Investor Services LLC, is entered into as of May 30, 2014.

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