0001104659-14-075993 Sample Contracts

SYNERGY PHARMACEUTICALS INC. AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of November 3, 2014 7.50% Convertible Senior Notes due 2019
Indenture • November 3rd, 2014 • Synergy Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

INDENTURE dated as of November 3, 2014 between SYNERGY PHARMACEUTICALS INC., a Delaware corporation, as issuer (the “Company,” as more fully set forth in Section 1.01) and WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee,” as more fully set forth in Section 1.01).

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