0001104659-15-002117 Sample Contracts

THE MEDICINES COMPANY AND WELLS FARGO BANK, NATIONAL ASSOCIATION, as Trustee INDENTURE Dated as of January 13, 2015 2.50% Convertible Senior Notes due 2022

Indenture • January 13th, 2015 • Medicines Co /De • Pharmaceutical preparations • New York

• Contract Type
  Indenture
• Filed
  January 13th, 2015
• Company
  Medicines Co /De
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

INDENTURE dated as of January 13, 2015 between THE MEDICINES COMPANY, a Delaware corporation, as issuer (the “Company”, as more fully set forth in Section 1.01) and WELLS FARGO BANK, NATIONAL ASSOCIATION, a national banking association, as trustee (the “Trustee”, as more fully set forth in Section 1.01).