0001104659-15-034943 Sample Contracts

To: AMAG Pharmaceuticals, Inc. Waltham, Massachusetts 02451 Attention: Mr. Frank E. Thomas: Executive Vice President, Chief Operating Officer Telephone No.: (617) 498-3377 Facsimile No.: (617) 588-0475 Re: Amendment to Warrants Transactions
Warrant Amendment • May 6th, 2015 • Amag Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This letter agreement (this “Amendment”) amends the terms and conditions of the transactions (the “Transactions”) evidenced by (i) the letter agreement re: Base Warrants between JPMorgan Chase Bank, National Association, London Branch (“Dealer”) and AMAG Pharmaceuticals, Inc. (“Company”) dated as of February 11, 2014 (as amended or modified prior to the date hereof, the “Base Confirmation”), and (ii) the letter agreement re: Additional Warrants between Dealer and Company dated as of February 13, 2014 (as amended or modified prior to the date hereof, the “Additional Confirmation” and together with the Base Confirmation, the “Confirmations”).

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FIRST AMENDMENT TO CREDIT AGREEMENT
Credit Agreement • May 6th, 2015 • Amag Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This FIRST AMENDMENT TO CREDIT AGREEMENT (this “Amendment”) is entered into as of March 31, 2015, among AMAG Pharmaceuticals, Inc., a Delaware corporation (the “Borrower”), each of the Lenders (as defined below) party hereto and Jefferies Finance LLC, as Administrative Agent (in such capacity, the “Administrative Agent”), and is acknowledged and consented to by each Subsidiary Guarantor.

FIRST AMENDMENT TO LEASE
Lease • May 6th, 2015 • Amag Pharmaceuticals Inc. • Pharmaceutical preparations

FIRST AMENDMENT TO LEASE dated as of this 24th day of March, 2015 (the “Effective Date”), by and between BP BAY COLONY LLC, a Delaware limited liability company (“Landlord”) and AMAG PHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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