0001104659-15-053179 Sample Contracts

AMENDMENT NO. 2
Commercial Supply Agreement • July 27th, 2015 • Amag Pharmaceuticals Inc. • Pharmaceutical preparations

This Amendment No. 2 (“Amendment”), effective as of March 31, 2015 (the “Effective Date”), entered into by and between (i) AMAG Pharmaceuticals, Inc. (“AMAG” or the “Company”) and (ii) Sigma-Aldrich, Inc. (“SAFC”), amends that certain Commercial Supply Agreement between AMAG and SAFC dated August 29, 2012 (the “Commercial Supply Agreement”), as amended October 3, 2013 (“Amendment No. 1”), and collectively with the Commercial Supply Agreement, the “Agreement”). Capitalized terms used but not defined in this Amendment will have the meanings given them in the Agreement.

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Re: Notice of Termination and Transition Service Agreement
Amag Pharmaceuticals Inc. • July 27th, 2015 • Pharmaceutical preparations

This letter confirms the ending of your employment with AMAG Pharmaceuticals, Inc. (the “Company”) and sets forth the terms of a mutually agreeable transition plan.

Re: Notice of Termination
Amag Pharmaceuticals Inc. • July 27th, 2015 • Pharmaceutical preparations

You and the Company entered into the Employment Agreement dated February 24, 2014 (“Employment Agreement”). To the extent that a term is not defined herein, the capitalized terms shall have the same meaning as in the Employment Agreement. Pursuant to Section 4(d) of the Employment Agreement the Company may elect to terminate your employment other than for Cause (as that term is defined in the Employment Agreement) upon thirty (30) days prior written notice to you. This letter serves as that written notice. Accordingly, you are hereby notified that your employment is being terminated effective June 3, 2015 (the “Date of Termination”).

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