0001104659-15-057216 Sample Contracts

Confidential Treatment Requested Under 17 C.F.R. §§ 200.80(b)(4) and 240-24b-2 WORK ORDER NO. 10
Development and Manufacturing Services Agreement • August 6th, 2015 • Radius Health, Inc. • Pharmaceutical preparations

THIS WORK ORDER NO. 10 is by and between RADIUS HEALTH, INC. (“RADIUS”) and LONZA Sales Ltd, a Swiss company having an address at Muenchensteinerstrasse 38, CH-4002 Basel, Switzerland (together with its Affiliates, “Manufacturer”), and upon execution will be incorporated into the Development and Manufacturing Services Agreement between RADIUS and Manufacturer dated October 16, 2007 (the “Agreement”). Capitalized terms in this Work Order will have the same meanings as set forth in the Agreement.

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Confidential Treatment Requested Under 17 C.F.R. §§ 200.80(b)(4) and 240-24b-2 Change Order Form # 26
Change Order • August 6th, 2015 • Radius Health, Inc. • Pharmaceutical preparations

Project Name: For the development of Radius’ Abaloparatide compound delivered via 3M’s Microstructured Transdermal Delivery System

Confidential Treatment Requested Under 17 C.F.R. §§ 200.80(b)(4) and 240-24b-2 WORK ORDER NO. 9
Work Order • August 6th, 2015 • Radius Health, Inc. • Pharmaceutical preparations

THIS WORK ORDER NO. 9 is by and between RADIUS HEALTH, INC. (“RADIUS”) and LONZA Sales Ltd, a Swiss company having an address at Muenchensteinerstrasse 38, CH-4002 Basel, Switzerland (together with its Affiliates, “Manufacturer”), and upon execution will be incorporated into the Development and Manufacturing Services Agreement between RADIUS and Manufacturer dated October 16, 2007 (the “Agreement”). Capitalized terms in this Work Order will have the same meanings as set forth in the Agreement.

CLINICAL TRIAL SERVICES AGREEMENT AMENDMENT NO. 3
Clinical Trial Services Agreement • August 6th, 2015 • Radius Health, Inc. • Pharmaceutical preparations

The parties wish to enter into this Amendment No. 3 effective as of July 8, 2015 (“Amendment Date”). Capitalized terms used in this Amendment No. 3 and not defined herein are used with the meanings ascribed to them in this Agreement.

Confidential Treatment Requested Under 17 C.F.R. §§ 200.80(b)(4) and 240-24b-2 WORK ORDER NO. 8
Development and Manufacturing Services Agreement • August 6th, 2015 • Radius Health, Inc. • Pharmaceutical preparations

THIS WORK ORDER NO. 8 is by and between RADIUS HEALTH, INC. (“RADIUS”) and LONZA Sales Ltd, a Swiss company having an address at Muenchensteinerstrasse 38, CH-4002 Basel, Switzerland (together with its Affiliates, “Manufacturer”), and upon execution will be incorporated into the Development and Manufacturing Services Agreement between RADIUS and Manufacturer dated October 16, 2007 (the “Agreement”). Capitalized terms in this Work Order will have the same meanings as set forth in the Agreement.

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