0001104659-16-090815 Sample Contracts

AMENDMENT TO FOURTH AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • January 21st, 2016 • Synergy Pharmaceuticals, Inc. • Pharmaceutical preparations • New York

This AMENDMENT (the “Amendment”) to the FOURTH AMENDED AND RESTATED EXECUTIVE EMPLOYMENT AGREEMENT (the “Agreement”) originally dated as of January 7, 2015, by and between Synergy Pharmaceuticals Inc., a Delaware corporation (the “Company”) and Gary S. Jacob, Ph.D. (the “Executive”) is dated as of January 18, 2016. Capitalized terms not defined herein shall have the meanings assigned to them in the Agreement.

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