0001104659-16-105213 Sample Contracts

November 30, 2015

Terms of Transition and Separation • March 15th, 2016 • Loxo Oncology, Inc. • Pharmaceutical preparations • California

• Contract Type
  Terms of Transition and Separation
• Filed
  March 15th, 2016
• Company
  Loxo Oncology, Inc.
• Industry
  Pharmaceutical preparations
• Jurisdiction
  California

This letter confirms the agreement (“Agreement”) between you and Loxo Oncology, Inc. (the “Company”) concerning the terms of your transition and separation from employment and offers you certain benefits to which you would not otherwise be entitled, conditioned upon your provision of a general release of claims and covenant not to sue now and upon the Separation Date (defined below) as provided herein. If you agree to the terms outlined herein, please sign and return this Agreement to me in the timeframe outlined below.

AMENDMENT NO. 5 TO DRUG DISCOVERY COLLABORATION AGREEMENT

Drug Discovery Collaboration Agreement • March 15th, 2016 • Loxo Oncology, Inc. • Pharmaceutical preparations

• Contract Type
  Drug Discovery Collaboration Agreement
• Filed
  March 15th, 2016
• Company
  Loxo Oncology, Inc.
• Industry
  Pharmaceutical preparations

THIS AMENDMENT NO.5 TO DRUG DISCOVERY COLLABORATION AGREEMENT (“Amendment”), effective February 18, 2016 (the “Amendment Date”), is by and between Array BioPharma Inc., a Delaware corporation (“Array”), and Loxo Oncology, Inc., a Delaware corporation (“Loxo”).