0001104659-16-163271 Sample Contracts

NOTE PURCHASE AGREEMENT
Note Purchase Agreement • December 21st, 2016 • Amicus Therapeutics Inc • Pharmaceutical preparations • Delaware

This NOTE PURCHASE AGREEMENT (this “Agreement”) is made as of the 15th day of December, 2016 by and among Redmile Capital Offshore Fund, Ltd. (the “Seller”), Amicus Therapeutics International Holding LTD (“Amicus International”) and Amicus Therapeutics, Inc. (the “Purchaser”).

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AMICUS THERAPEUTICS, INC. (Company) WILMINGTON TRUST, NATIONAL ASSOCIATION (Trustee) 3.00% Convertible Senior Notes due 2023 INDENTURE Dated as of December 21, 2016
Indenture • December 21st, 2016 • Amicus Therapeutics Inc • Pharmaceutical preparations • New York

INDENTURE, dated as December 21, 2016, between Amicus Therapeutics, Inc., a Delaware corporation, as issuer (the “Company”), and Wilmington Trust, National Association, a national banking association, as trustee (the “Trustee”).

NOTE PURCHASE AGREEMENT
Note Purchase Agreement • December 21st, 2016 • Amicus Therapeutics Inc • Pharmaceutical preparations • Delaware

This NOTE PURCHASE AGREEMENT (this “Agreement”) is made as of the 15th day of December, 2016 by and among Redmile Capital Offshore Fund II, Ltd. (the “Seller”), Amicus Therapeutics International Holding LTD (“Amicus International”) and Amicus Therapeutics, Inc. (the “Purchaser”).

NOTE PURCHASE AGREEMENT
Note Purchase Agreement • December 21st, 2016 • Amicus Therapeutics Inc • Pharmaceutical preparations • Delaware

This NOTE PURCHASE AGREEMENT (this “Agreement”) is made as of the 15th day of December, 2016 by and among GCM Grosvenor Special Opportunities Master Fund, Ltd. (the “Seller”), Amicus Therapeutics International Holding LTD (“Amicus International”) and Amicus Therapeutics, Inc. (the “Purchaser”).

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