0001104659-17-024205 Sample Contracts

FORM OF SUPPORT AGREEMENT
Support Agreement • April 18th, 2017 • Nivalis Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This SUPPORT AGREEMENT (this “Agreement”), dated as of [·], 2017, is by and between Alpine Immune Sciences, Inc., a Delaware corporation (the “Company”), and the Person set forth on Schedule A (the “Stockholder”).

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FORM OF SUPPORT AGREEMENT
Support Agreement • April 18th, 2017 • Nivalis Therapeutics, Inc. • Pharmaceutical preparations • Delaware

This SUPPORT AGREEMENT (this “Agreement”), dated as of [•], 2017, is by and between Nivalis Therapeutics, Inc., a Delaware corporation (the “Company”), and the Persons set forth on Schedule A (each such Person a “Stockholder” and collectively the “Stockholders”).

AGREEMENT AND PLAN OF MERGER AND REORGANIZATION among: NIVALIS THERAPEUTICS, INC., a Delaware corporation; NAUTILUS MERGER SUB, INC., a Delaware corporation; and ALPINE IMMUNE SCIENCES, INC., a Delaware corporation Dated as of April 18, 2017
Merger Agreement • April 18th, 2017 • Nivalis Therapeutics, Inc. • Pharmaceutical preparations • Delaware

THIS AGREEMENT AND PLAN OF MERGER AND REORGANIZATION (this “Agreement”) is made and entered into as of April 18, 2017, by and among NIVALIS THERAPEUTICS, INC., a Delaware corporation (“Nautilus”), NAUTILUS MERGER SUB, INC., a Delaware corporation and wholly owned subsidiary of Nautilus (“Merger Sub”), and ALPINE IMMUNE SCIENCES, INC., a Delaware corporation (the “Company”). Certain capitalized terms used in this Agreement are defined in Exhibit A.

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