SYROS PHARMACEUTICALS, INC. 4,188,481 shares of common stock, par value $0.001 per share (the “Common Stock”) Underwriting AgreementUnderwriting Agreement • January 31st, 2018 • Syros Pharmaceuticals, Inc. • Pharmaceutical preparations • New York
Syros Pharmaceuticals, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters listed in Schedule 1 hereto (the “Underwriters”), for whom you are acting as representatives (the “Representatives”), an aggregate of 4,188,481 shares of Common Stock of the Company (the “Underwritten Shares”) and, at the option of the Underwriters, up to an additional 628,272 shares of Common Stock of the Company (the “Option Shares”). The Underwritten Shares and the Option Shares are herein referred to as the “Shares”. The shares of Common Stock of the Company to be outstanding after giving effect to the sale of the Shares are referred to herein as the “Stock”.
