0001104659-20-001367 Sample Contracts

FIRST SUPPLEMENTAL INDENTURE

Supplemental Indenture • January 6th, 2020 • Medicines Co /De • Pharmaceutical preparations • New York

• Contract Type
  Supplemental Indenture
• Filed
  January 6th, 2020
• Company
  Medicines Co /De
• Industry
  Pharmaceutical preparations
• Jurisdiction
  New York

FIRST SUPPLEMENTAL INDENTURE, dated as of January 6, 2020 (this “Supplemental Indenture”), by and between THE MEDICINES COMPANY, a Delaware corporation, as issuer (the “Company”), and WELLS FARGO BANK, NATIONAL ASSOCIATION, as trustee (the “Trustee”), supplements the Indenture, dated as of December 18, 2018 (the “Indenture”), between the Company and the Trustee.