0001104659-21-137429 Sample Contracts

1,132,111 CLASS A ORDINARY SHARES IN THE FORM OF AMERICAN DEPOSITARY SHARES of ANPAC BIO-MEDICAL SCIENCE CO., LTD. UNDERWRITING AGREEMENT
Underwriting Agreement • November 12th, 2021 • AnPac Bio-Medical Science Co., Ltd. • Services-medical laboratories • New York

It is understood that the several Underwriters are to make a public offering of the Public Shares as soon as the Representative deems it advisable to do so. The Public Shares are to be initially offered to the public at the public offering price set forth in the Prospectus Supplement. The Representative will take delivery of the Public Shares in the form of American Depositary Shares. The American Depositary Shares are to be issued pursuant to the Amended and Restated Deposit Agreement dated as of February 3, 2021 (the “Deposit Agreement”) among the Company, Citibank N.A. (the “Depositary”) and the owners and holders from time to time of the American Depositary Shares issued under the Deposit Agreement. Each American Depositary Share will represent the right to receive one Ordinary Share deposited pursuant to the Deposit Agreement. The Ordinary Shares of the Company represented by the ADSs may hereinafter be referred to as the “Underlying Securities.”

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