0001104659-22-006027 Sample Contracts

AMENDMENT NO. 1 TO SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • January 20th, 2022 • Scopus BioPharma Inc. • Pharmaceutical preparations • New York

AMENDMENT NO. 1 TO SECURITIES PURCHASE AGREEMENT, dated as of January 14, 2022 (this “Amendment”), among SCOPUS BIOPHARMA INC., a Delaware corporation (the “Company”) and the Purchaser signatory hereto. Capitalized terms used and not otherwise defined herein shall have the meanings set forth in the Purchase Agreement, as defined herein.

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AMENDMENT NO. 1 TO REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • January 20th, 2022 • Scopus BioPharma Inc. • Pharmaceutical preparations

AMENDMENT NO. 1 TO REGISTRATION RIGHTS AGREEMENT, dated as of January 14, 2022 (this “Amendment”), among SCOPUS BIOPHARMA INC., a Delaware corporation (the “Company”) and the holder signatory hereto (the “Holder”). Capitalized terms used and not otherwise defined herein shall have the meanings set forth in the Registration Rights Agreement, as defined herein.

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