0001104659-22-006034 Sample Contracts

INDEMNIFICATION AGREEMENT
Indemnification Agreement • January 20th, 2022 • Gelesis Holdings, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of January 13, 2022 by and between Gelesis Holdings, Inc., a Delaware corporation (the “Company”), and [ ] (“Indemnitee”).

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July 16, 2021 Yishai Zohar Brookline, MA 02445 Re: Employment Agreement Dear Yishai:
Employment Agreement • January 20th, 2022 • Gelesis Holdings, Inc. • Pharmaceutical preparations • Massachusetts

On behalf of Gelesis, Inc. (the “Company”), I am pleased to confirm our offer to continue your employment as Chief Executive Officer (“CEO”) and Founder of the Company. The terms and conditions of your continued employment are set forth below in this letter agreement (the “Agreement”):

AMENDED AND RESTATED REGISTRATION AND STOCKHOLDER RIGHTS AGREEMENT
Registration and Stockholder Rights Agreement • January 20th, 2022 • Gelesis Holdings, Inc. • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED REGISTRATION AND STOCKHOLDER RIGHTS AGREEMENT (this “Agreement”) is dated as of January 13, 2022, and is by and among Gelesis Holdings, Inc., a Delaware corporation (the “Company”) (formerly known as Capstar Special Purpose Acquisition Corp.), Capstar Sponsor Group, LLC, a Delaware limited liability company (the “Sponsor”), the persons and entities listed on Exhibit A who hold beneficially and of record the type and number of securities (the “Sponsor Securities”) indicated next to their name in Exhibit A (each, a “Capstar Holder”) and certain former stockholders of Gelesis, Inc., a Delaware corporation and the entity that was merged with and into the Merger Sub (as defined below) contemporaneously with the execution and delivery of this Agreement (“Target”), listed on Exhibit B who hold beneficially and of record the type and number of shares of Common Stock, including Earn-Out Shares, and/or Equity Awards exercisable for shares of Common Stock (all as defined

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