0001104659-22-038338 Sample Contracts

SECOND AMENDMENT AGREEMENT
Second Amendment Agreement • March 28th, 2022 • Quoin Pharmaceuticals, Ltd. • Surgical & medical instruments & apparatus • New York

SECOND AMENDMENT AGREEMENT (this "Agreement"), dated as of March 13, 2022 (the “Effective Date”) by and among Quoin Pharmaceuticals, Inc., a Delaware corporation, with headquarters located at 42127 Pleasant Forest Ct, Ashburn, VA 20148 ("Quoin"), Quoin Pharmaceuticals Ltd. (formerly known as Cellect Biotechnology Ltd.), an Israeli company, with headquarters located at Azrieli Center, Round Tower, 30th Floor, 132 Menachem Begin Blvd, Tel Aviv, 6701101 (the "Company"), and the investor listed on the signature page attached hereto (the "Holder"). Capitalized terms used herein and not otherwise defined herein shall have the respective meanings set forth in the Primary Financing SPA, the Bridge SPA, the RRA or the Warrants (each as defined below), as applicable.

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