0001104659-22-110606 Sample Contracts

GLOBAL AMENDMENT
Global Amendment • October 21st, 2022 • Jaguar Health, Inc. • Pharmaceutical preparations

This Global Amendment (this “Amendment”) is entered into as of October 17, 2022, by and among Streeterville Capital, LLC, a Utah limited liability company (“Lender”), Jaguar Health, Inc., a Delaware corporation (“Company”), and Napo Pharmaceuticals, Inc., a Delaware corporation (“Napo”, and together with Company, “Borrower”). Capitalized terms used but not otherwise defined herein shall have the meanings ascribed to such terms in the Note (as defined below).

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