0001104659-23-039764 Sample Contracts

Purchase and Sale Agreement By and Between Milestone Pharmaceuticals Inc. and RTW Royalty I DAC Dated as of [●], 2023
Purchase and Sale Agreement • March 31st, 2023 • Milestone Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This PURCHASE AND SALE AGREEMENT, dated as of March 27, 2023 (this “Agreement”), is made and entered into by and between RTW Royalty I DAC, a designated activity company incorporated under the laws of Ireland with registered number 734869 and registered address at 2nd Floor, Palmerston House, Denzille Lane, Dublin 2, D02 WD37, Ireland (the “Buyer”), and Milestone Pharmaceuticals Inc., a Quebec corporation (the “Seller”).

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NOTE PURCHASE AGREEMENT
Note Purchase Agreement • March 31st, 2023 • Milestone Pharmaceuticals Inc. • Pharmaceutical preparations • New York

This Note Purchase Agreement (this “Agreement”) is entered into as of March 27, 2023 (the “Execution Date”) by and among Milestone Pharmaceuticals Inc., a corporation existing under the Business Corporations Act (Québec) (the “Company”), the purchasers from time to time party hereto (each, a “Purchaser”, and collectively, the “Purchasers”), RTW Investments, LP, as agent for the Purchasers (in such capacity, the “Principal Purchaser”) and Acquiom Agency Services LLC, as collateral agent for the Purchasers (in such capacity, the “Collateral Agent”).

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