0001104659-23-080013 Sample Contracts

20,000,000 Shares Iovance Biotherapeutics, Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • July 11th, 2023 • Iovance Biotherapeutics, Inc. • Biological products, (no disgnostic substances) • New York

The foregoing will not apply to (i) the registration of the offer and sale of the Shares, and the sale of the Shares to the Underwriters, in each case as contemplated by the Underwriting Agreement, (ii) the exercise of any option, warrant or other right to acquire shares of common stock of the Company, the settlement of any stock-settled stock appreciation rights, restricted stock or restricted stock units, or the conversion of any convertible security into securities of the Company; provided that any securities received as a result thereof by the undersigned will also be subject to the restrictions in this letter agreement, (iii) establishment of a trading plan meeting the requirements of Rule 10b5-1 under the Exchange Act for the transfer of Shares, if then permitted by the Company and applicable law; provided that such plan does not provide for any sales or transfers of Shares during the Lock-up Period, (iv) the transfer of Shares or Related Securities by gift, (v) the transfer of S

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