0001104659-24-008573 Sample Contracts

10,340,000 Shares of Common Stock Astria Therapeutics, Inc. UNDERWRITING AGREEMENT
Underwriting Agreement • January 31st, 2024 • Astria Therapeutics, Inc. • Pharmaceutical preparations • New York

Astria Therapeutics, Inc., a Delaware corporation (the “Company”), proposes to issue and sell to the several underwriters named in Schedule A (the “Underwriters”) an aggregate of 10,340,000 shares (the “Shares”) of its common stock, par value $0.001 per share (the “Common Stock”). Jefferies LLC (“Jefferies”) and Evercore Group L.L.C. (“Evercore”) have agreed to act as representatives of the several Underwriters (in such capacity, the “Representatives”) in connection with the offering and sale of the Shares. To the extent there are no additional underwriters listed on Schedule A, the term “Representatives” as used herein shall mean you, as Underwriters, and the term “Underwriters” shall mean either the singular or the plural, as the context requires.

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