0001104659-24-111473 Sample Contracts

ProQR Therapeutics N.V. 18,000,000 Ordinary Shares UNDERWRITING AGREEMENT Dated: October 22, 2024 ProQR Therapeutics N.V. 18,000,000 Ordinary Shares UNDERWRITING AGREEMENT
Underwriting Agreement • October 25th, 2024 • ProQR Therapeutics N.V. • Pharmaceutical preparations • New York
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SHARE PURCHASE AGREEMENT
Share Purchase Agreement • October 25th, 2024 • ProQR Therapeutics N.V. • Pharmaceutical preparations • New York

This Share Purchase Agreement (this “Agreement”) is entered into as of October 22, 2024 (the “Execution Date”), by and between ProQR Therapeutics N.V., a public company with limited liability (naamloze vennootschap) incorporated under the laws of The Netherlands (“ProQR”), and Eli Lilly and Company, a corporation organized and existing under the laws of Indiana, with its principal business office located at Lilly Corporate Center, Indianapolis, Indiana 46285, U.S.A. (“Lilly”). ProQR and Lilly are each hereafter referred to individually as a “Party” and together as the “Parties.” The capitalized terms used herein and not otherwise defined have the meanings given to them in Appendix 1 attached hereto or the Amended and Restated Collaboration Agreement.

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