0001113481-14-000032 Sample Contracts

SIXTH AMENDMENT TO SECOND AMENDED AND RESTATED DISTRIBUTION AGREEMENT
Distribution Agreement • May 12th, 2014 • Medicines Co /De • Pharmaceutical preparations

This Sixth Amendment to Second Amended and Restated Distribution Agreement (this “Amendment”) is between The Medicines Company, a Delaware corporation with offices at 8 Sylvan Way, Parsippany, NJ 07054 (“MDCO”), and Integrated Commercialization Solutions, Inc., a California corporation with offices at 3101 Gaylord Parkway, Frisco, TX 75034 (“Distributor”). This Amendment is effective as of February 01, 2014 (the “Amendment Effective Date”). MDCO and Distributor shall, at times throughout this Amendment, be referred to individually as a “Party” and collectively as the “Parties”.

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