0001113481-15-000048 Sample Contracts

AMENDMENT NO. 2 TO SUPPLY AGREEMENT By and between Teva API Inc. and The Medicines Company
Supply Agreement • November 9th, 2015 • Medicines Co /De • Pharmaceutical preparations

THIS AMENDMENT NO. 2 (“Second Amendment”) to the Supply Agreement, as defined below, is made and entered into as of July 1, 2015 (the “Effective Date”) by and between Teva API, Inc. (formerly known as Plantex USA Inc.), a New Jersey corporation with offices at 400 Chestnut Ridge Road, Woodcliff Lake, NJ 07670 (“TEVA”) and The Medicines Company, a Delaware corporation with offices at 8 Sylvan Way, Parsippany, NJ 07054 (“MDCO”). TEVA and MDCO are sometimes together referred to herein as the “Parties” and separately as a “Party.”

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SUPPLY AND DISTRIBUTION AGREEMENT
Supply and Distribution Agreement • November 9th, 2015 • Medicines Co /De • Pharmaceutical preparations • Delaware

This SUPPLY AND DISTRIBUTION AGREEMENT (“Agreement”), dated as of July 2, 2015, is made by and between The Medicines Company, a company with its principal offices located at 8 Sylvan Way, Parsippany, NJ 07054 (“Innovator”), and Sandoz Inc., a Colorado corporation with a corporate address at 100 College Road West, Princeton, NJ 08540 (“Sandoz”).

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