0001136261-19-000099 Sample Contracts

FOURTH AMENDMENT AGREEMENT
Fourth Amendment Agreement • March 8th, 2019 • Seelos Therapeutics, Inc. • Pharmaceutical preparations • New York

FOURTH AMENDMENT AGREEMENT, dated as of March 7, 2019 (this "Agreement"), by and among Seelos Corporation (formerly known as Seelos Therapeutics, Inc.), a Delaware corporation ("Seelos Delaware"), Seelos Therapeutics, Inc. (formerly known as Apricus Biosciences, Inc.), a Nevada corporation ("Seelos Nevada" and collectively, the combined and surviving company with Seelos Delaware, the "Company"), and the investor listed on the signature pages attached hereto (the "Investor"). All terms used and not defined herein are used as defined in the Securities Purchase Agreement and the Warrants (each as defined below), as applicable.

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