ContractDevelopment and License Agreement • August 4th, 2014 • Isis Pharmaceuticals Inc • Pharmaceutical preparations
AMENDMENT #5 TO THE RESEARCH, DEVELOPMENT AND LICENSE AGREEMENTDevelopment and License Agreement • August 4th, 2014 • Isis Pharmaceuticals Inc • Pharmaceutical preparations • Delaware
This AMENDMENT #5 TO THE RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT (this "Amendment No. 5") is entered into and made effective as of the 27th day of June, 2014 (the "Amendment No. 5 Effective Date") by and between Isis Pharmaceuticals, Inc., a Delaware corporation, having its principal place of business at 2855 Gazelle Court, Carlsbad, CA 92010 ("Isis"), and Glaxo Group Limited, a company existing under the laws of England and Wales, having its registered office at 980 Great West Road, Brentford London TW8 9GS, United Kingdom ("GGL"), and GlaxoSmithKline Intellectual Property Development Limited, a company existing under the laws of England and Wales, having its registered office at 980 Great West Road, Brentford London TW8 9GS, United Kingdom ("GSK IPDL"). GGL and GSK IPDL are referred to together as "GSK". Isis and GSK are each referred to herein by name or as a "Party" or, collectively, as "Parties."
AMENDMENT #4 TO RESEARCH, DEVELOPMENT AND LICENSE AGREEMENTDevelopment and License Agreement • August 4th, 2014 • Isis Pharmaceuticals Inc • Pharmaceutical preparations
This AMENDMENT #4 TO THE RESEARCH, DEVELOPMENT AND LICENSE AGREEMENT (this "Amendment No. 4") is entered into and made effective as of the 10th day of April, 2014 (the "Amendment No. 4 Effective Date") by and between Isis Pharmaceuticals, Inc., a Delaware corporation, having its principal place of business at 2855 Gazelle Court, Carlsbad, CA 92010 ("Isis"), and Glaxo Group Limited, a company existing under the laws of England and Wales, having its registered office at 980 Great West Road, Brentford London TW8 9GS, United Kingdom ("GSK"). Isis and GSK are each referred to herein by name or as a "Party" or, collectively, as "Parties."
