0001140361-22-025945 Sample Contracts

THIRD AMENDMENT TO COLLABORATION AGREEMENT
Collaboration Agreement • July 13th, 2022 • Innoviva, Inc. • Pharmaceutical preparations • Delaware

This Amendment to Collaboration Agreement (this “Amendment”) is entered into as of July 13, 2022 and effective as of the date of the Theravance Closing (as defined below) (such date, the “Third Amendment Effective Date”), by and among (i) Innoviva, Inc. (f/k/a Theravance, Inc.), a Delaware corporation (“Innoviva”), (ii) Glaxo Group Limited, a private company limited by shares registered under the laws of England and Wales (“GSK”), and (iii) Theravance Respiratory Company, LLC, a Delaware limited liability company (“TRC”). This Amendment amends the Collaboration Agreement by and between Innoviva and GSK, dated as of November 14, 2002, as amended on April 11, 2006 (the “First Amendment”) and March 3, 2014 (the “Second Amendment”) (such agreement, as amended, the “Collaboration Agreement”). Innoviva, GSK and TRC are referred to in this Amendment individually as a “Party” and collectively as the “Parties”.

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EQUITY PURCHASE AGREEMENT BY AND AMONG INNOVIVA TRC HOLDINGS LLC, ROYALTY PHARMA INVESTMENTS 2019 ICAV AND SOLELY FOR THE PURPOSE OF SECTIONS 9.1, 9.3, 9.11 AND 9.12, INNOVIVA, INC. JULY 13, 2022
Equity Purchase Agreement • July 13th, 2022 • Innoviva, Inc. • Pharmaceutical preparations • New York

This EQUITY PURCHASE AGREEMENT, dated as of July 13, 2022 (this “Agreement”), is entered into by and between Innoviva TRC Holdings LLC, a Delaware limited liability company and an indirect wholly-owned subsidiary of Parent (the “Seller”), Royalty Pharma Investments 2019 ICAV, an Irish collective asset-management vehicle (the “Purchaser”) and, solely for the purpose of Sections 9.1, 9.3, 9.11 and 9.12, Innoviva, Inc. (formerly known as Theravance, Inc.) (the “Parent”). Capitalized terms used but not otherwise defined herein shall have the meanings ascribed to them in Section 1 below.

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