0001144204-07-016526 Sample Contracts

OMNIBUS AMENDMENT AND CONSENT
Omnibus Amendment and Consent • April 2nd, 2007 • Acura Pharmaceuticals, Inc • Pharmaceutical preparations • New York

OMNIBUS AMENDMENT AND CONSENT EFFECTIVE AS OF March 30, 2007 (this “Omnibus Amendment and Consent”) by and among Acura Pharmaceuticals, Inc. (the “Company”), and Acura Pharmaceutical Technologies, Inc. and the following lenders (“Lenders”): Galen Partners III, L.P. (as agent for the other lenders (“Agent”) and as a lender itself), Galen Partners International, III, L.P., Galen Employee Fund III, L.P., Care Capital Offshore Investments II, LP, Care Capital Investments II, LP, Essex Woodlands Health Ventures V, L.P. (the foregoing Lenders, being the “VC Lenders”), Dennis Adams, George E. Boudreau, Michael Weisbrot, Susan Weisbrot; and the following persons with respect to Sections 5, 6, 7, and 8: John E. Heppe Jr. and Peter Steiglitz (“Additional Watson Holders”).

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