0001144204-07-063388 Sample Contracts

AMENDMENT NO. 1 TO DEPOSIT AGREEMENT
Deposit Agreement • November 20th, 2007 • Bioprogress PLC • Pharmaceutical preparations • New York

AMENDMENT NO. 1, dated as of November 20, 2007 (the “Amendment”), to the Deposit Agreement dated as of October 20, 2004 (as so amended hereby, the "Deposit Agreement"), among Meldex International plc (fka BioProgress plc), a company incorporated in England and Wales (the "Company"), JPMorgan Chase Bank, N.A., as depositary (the "Depositary"), and all Holders from time to time of American Depositary Receipts issued thereunder ("ADRs") evidencing American Depositary Shares ("ADSs") representing deposited Shares.

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