0001144204-07-064880 Sample Contracts

AMENDMENT NO. 4 TO DEPOSIT AGREEMENT
Deposit Agreement • November 29th, 2007 • Novo Nordisk a S • Pharmaceutical preparations

AMENDMENT No. 4 dated as of November 29, 2007 (the "Amendment") to the Deposit Agreement dated as of February 1, 1981, as amended as of September 10, 1984, as further amended and restated as of May 1, 1991 and as amended as of April 15, 1994, December 21, 1996 and April 4, 2001 (as so amended, the "Deposit Agreement"), among Novo Nordisk A/S, incorporated under the laws of Denmark (the "Company"), JPMorgan Chase Bank, N.A. (fka Morgan Guaranty Trust Company of New York), as depositary (the "Depositary"), and all Holders from time to time of American Depositary Receipts issued thereunder.

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