0001144204-08-061039 Sample Contracts

SECOND AMENDMENT TO RIGHTS AGREEMENT
Rights Agreement • November 4th, 2008 • Imclone Systems Inc • Biological products, (no disgnostic substances)

SECOND AMENDMENT TO RIGHTS AGREEMENT, dated as of October 31, 2008 (this “Amendment”), between ImClone Systems Incorporated, a Delaware corporation (the “Company”) and Computershare Trust Company, N.A. (formerly known as EquiServe Trust Company, N.A.) as Rights Agent (the “Rights Agent”).

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