0001144204-10-066381 Sample Contracts

25,000,000 Common Shares YM BIOSCIENCES INC. UNDERWRITING AGREEMENT
Underwriting Agreement • December 14th, 2010 • Ym Biosciences Inc • Pharmaceutical preparations • New York

YM BioSciences Inc. (the “Company”), a corporation continued under the Nova Scotia Companies Act (the “NSCA”), proposes, subject to the terms and conditions stated herein, to issue and sell to the underwriters listed on Schedule I hereto (the “Underwriters”), for whom Roth Capital Partners, LLC is acting as representative (the “Representative”), 25,000,000 authorized but unissued shares (the “Firm Shares”) of the Company’s common shares, without nominal or par value (the “Common Shares”). The Company has granted to the Underwriters an option to purchase up to an aggregate of 3,750,000 additional Common Shares (the “Additional Shares”) as may be necessary to cover over-allotments made in connection with the offering. The Firm Shares and the Additional Shares are collectively referred to as the “Shares.” The offering of the Shares as contemplated hereby is referred to herein as the “Offering.”

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